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Specifications
- Antibody type:Primary
- Antigen name:Cytochrome P450, Family 17, Subfamily A, Polypeptide 1
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:CYP17A1
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:steroid 17-alpha-monooxygenase,17?-hydroxylase/17,20 lyase/17,20 desmolase|CYP17|S17AH|P450C17|CPT7
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Supplier No.:14447-1-AP
Specifications
About this item
The human cytochrome P450c17 enzyme is encoded by the CYP17A1 gene. It is the qualitative regulator of steroidogenesis in the human adrenals.In its absence, aldosterone is produced in the human adrenal zona glomerulosa .The CYP17A1 gene is expressed in the adrenal cortex and the gonads but not in the placenta . Although CYP17A1 has been shown to be a 50-kDa protein, the presence of a lower molecular mass(30 kDa) immunoreactive form in rat Ley- dig cells was previously shown and it is either a degradation product or a truncated form of the 50 kDa enzyme. Defects in CYP17A1 are the cause of adrenal hyperplasia type 5 (AH5).
Western Blot: HeLa Cells, 1:200-1:1000; IHC: Human Prostate Cancer Tissue, 1:20-1:200; IF: HepG2 Cells, 1:20-1:200
Type: Primary
Antigen: CYP17A1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: