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Specifications
- Antibody type:Primary
- Antigen name:Caspase 8
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:CASP8
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:FLICE|caspase 8|MACH-beta-1/2/3/4 protein|FADD-homologous ICE/CED-3-like protease|MCH5|apoptotic protease Mch-5|FADD-like ICE|MACH-alpha-1/2/3 protein|CAP4|ALPS2B|apoptotic cysteine protease|Casp-8|MORT1-associated ced-3 homolog|caspase-8|apoptosis-related cysteine protease|ICE-like apoptotic protease 5|MACH
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. no.:10084-096
- Supplier No.:13423-1-AP
Specifications
About this item
CASP8, also named as MCH5, MACH, FLICE, and CAP4, belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. CASP8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3. It may control diabetic embryopathy-associated apoptosis via regulation of the Bid-stimulated mitochondrion/caspase-9 pathway. CASP8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa.
Western Blot: HepG2 Cells, 1:200-1:2000; IHC: Human Lymphoma Tissue, 1:20-1:200; IP: HeLa Cells, 1:200-1:2000; IF: HepG2 Cells, 1:10-1:100
Type: Primary
Antigen: CASP8
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human