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Specifications
- Antibody type:Primary
- Antigen name:Zinc Finger, FYVE Domain Containing 16
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:ZFYVE16
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:B130024H06Rik|mKIAA0305|AI035632|B130031L15
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. no.:10097-272
- Supplier No.:13118-2-AP
Specifications
About this item
Endofin (also known as ZFYVE16) is an endosomal FYVE domian protein implicated in regulating membrane trafficking. Endofin has been shown to localize to early endosomes. It co-localizes with SARA but does not associate with it or Smad2 and does not behave like SARA in affecting TGF-signaling. Northern blot analysis showed ZFYVE16 was widely expressed with high levels in kidney, placenta and lung. Overexpression of Endofin causes endosome aggregation. The gene of ZFYVE16 maps to chromosome 5q14, and encodes a 1539-amino acid protein with a molecular mass of 169 kDa. In addition, endogenous Endofin can also be detected as a band of 230-250 kDa.
- Western Blot: MDA-MB-453s Cells, 1:500-1:5000; IP: HeLa Cells, 1:200-1:2000; IHC: Human Kidney Tissue, 1:20-1:200
Type: Primary
Antigen: ZFYVE16
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat