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Specifications
- Antibody type:Primary
- Antigen name:Proteasome (prosome macropain) 26S Subunit non-ATPase 14
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:PSMD14
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:PAD1|RPN11|POH1
- Storage buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. no.:10092-972
- Supplier No.:12059-1-AP
Specifications
About this item
The PSMD14 (POH1, also known as Rpn11/MPR1/S13/CepP1) protein is a metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. PSMD14 is highly expressed in heart and skeletal muscle. In carcinoma cell lines. down-regulation of PSMD14 by siRNA transfection had a considerable impact on cell viability causing cell arrest in the G0-G1 phase, ultimately leading to senescence.
Western Blot: Human Heart Tissue, 1:200-1:2000; IHC: Human Colon cancer, 1:20-1:200
Type: Primary
Antigen: PSMD14
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat