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Specifications
- Antibody type:Primary
- Antigen name:Pellino E3 Ubiquitin Protein Ligase 1
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:PELI1
- Conjugation:Unconjugated
- ELISA:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:Pellino-related intracellular-signaling molecule|Pellino 1|PRISM|Pellino-1|E3 ubiquitin-protein ligase pellino homolog 1
- Storage buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. no.:10092-078
- Supplier No.:12053-1-AP
Specifications
About this item
PELI1 encodes pellino-1, an E3 ubiquitin-protein ligase pellino homolog. E3 ubiquitin ligase functions by catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Pellino-1 is involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Pellino-1 can mediate 'Lys-63'-linked polyubiquitination of IRAK1 allowing subsequent NF-kappa-B activation thus playing a role in cellular inflammation. This antibody may cross react with Pellino-3.
Western Blot: Mouse Thymus Tissue, 1:500-1:5000
Type: Primary
Antigen: PELI1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat