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Specifications
- Antibody type:Primary
- Antigen name:Small ubiquitin-related modifier 2 And 3
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:SUMO2 + SUMO3
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:SUMO-2|ubiquitin-like protein SMT3A|SMT3 homolog 1|Sumo3|ubiquitin-like protein SMT3B|SMT3H1|SMT3 suppressor of mif two 3 homolog 1|Smt3B|SUMO-3|SMT3A|small ubiquitin-related modifier 3|SUMO2
- Storage buffer:PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. no.:10082-234
- Supplier No.:11251-1-AP
Specifications
About this item
Ubiquitin is most famous for its function in targeting proteins for degradation by the 26S proteasome, ubiquitin needs to be attached to a substrate in chains (polyubiquitylation) before being recognized by proteasome. Similarly, SUMO (small ubiquitin-related modifier) can be linked to substrates in chains (polysumoylation), SUMO modification has been implicated in many important cellular processes including the control of genome stability, signal transduction, targeting to and formation of nuclear compartments, cell cycle and meiosis. There are 4 confirmed SUMO isoforms in human, SUMO-1, SUMO-2, SUMO-3 and SUMO-4. SUMO-2 and SUMO-3 are nearly identical but are distinct from SUMO-1. SUMO2/3 conjugation was recently widely involved in neuroprotective activities. A substitution (M55V) of SUMO4 was strongly associated with the pathogenesis of type 1 diabetes (T1D) involving NF kappa B related mechanisms.
Western Blot:Apoptosised HeLa Cells, 1:200-1:1000; IHC: Human gliomas Tissue, 1:20-1:200
Type: Primary
Antigen: SUMO2 + SUMO3
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat