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Specifications
- Antibody type:Primary
- Antigen name:Poly(A) Binding Protein Interacting Protein 1
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Monkey,Human,Rat,Mouse
- Antigen symbol:PAIP1
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoFluorescence:Yes
- Size:150 µL
- Western blot:Yes
- Storage buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. no.:10091-752
- Supplier No.:10675-1-AP
Specifications
About this item
In initiation of translation in eukaryotes, binding of the small ribosomal subunit to mRNA requires recognition of the 5-prime cap structure by the cap-binding complex eIF4F. eIF4F consists of eIF4E, eIF4A, and eIF4G. Translation initiation is further regulated by the mRNA 3-prime poly(A) tail and the poly(A)-binding protein (PABC1). PAIP1 interacts with PABC1 and some eIF4 complexes . It is a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs, and associates with EIF4A and PABPC1 may potentiate contacts between mRNA termini .
Western Blot: HeLa Cells, 1:500-1:5000; IF: MCF-7 Cells, 1:20-1:200
Type: Primary
Antigen: PAIP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Monkey