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Specifications
- Antibody type:Primary
- Antigen name:Matrix Metalloproteinase 1
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:MMP1
- Conjugation:Unconjugated
- ELISA:Yes
- Flow cytometry:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:interstitial collagenase|matrix metalloprotease 1|CLGN|CLG|fibroblast collagenase|matrix metalloproteinase 1
- Storage buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. no.:10089-668
- Supplier No.:10371-2-AP
Specifications
About this item
MMP1, also named as CLG, belongs to the peptidase M10A family. MMP is the main enzyme that cleaves fibrillar collagen, namely types I, II, III, VII, and X.It is involved in cell migration and invasion, and is frequently up-regulated in cancer cells. It can be cleavage to two major forms (22 kDa and 27 kDa) by undergoing autolytic,and the minor form (25 kDa) is the glycosylated form of the 22 kDa form. The 27 kDa form has no activity while the 22/25 kDa form can act as activator for collagenase.The sizes of pro-MMP-1 and active MMP-1 from human synovial fibroblasts have been reported as 52 to 56 kDa, depending on glycosylation, and 41 to 45 kDa, respectively.In addition ,a band of 62-kDa observed in the current study is pro-MMp-1.
Western Blot:A549 Cells, 1:200-1:2000; IHC: Human cervical cancer Tissue, 1:20-1:200; IF: HepG2 Cells, 1:20-1:200; IP:A549 Cells, 1:500-1:5000; FC: HepG2 Cells, N/A
Type: Primary
Antigen: MMP1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat