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Specifications
- Antibody type:Primary
- Antigen name:Melanophilin
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:MLPH
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- ImmunoPrecipitation:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:l1Rk3|5031433I09Rik|l(1)-3Rk|D1Wsu84e|AW228792|2210418F23Rik|ln|Slac-2a
- Storage buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Antigen affinity Purification
- Cat. no.:10090-138
- Supplier No.:10338-1-AP
Specifications
About this item
Melanophilin (Mlph) is a member of the exophilin subfamily of Rab effector proteins. MLPH is a modular protein, forming a ternary complex with the small Ras-related GTPase Rab27A in its GTP-bound form and the motor protein myosin Va. It regulates retention of melanosomes at the peripheral actin cytoskeleton of melanocytes, a process essential for normal mammalian pigmentation. Defects in MLPH are a cause of Griscelli syndrome type 3 (GS3), which is characterized by a silver-gray hair color and abnormal pigment distribution in the hair shaft.
Western Blot:A375 Cells, 1:200-1:2000; IHC: Human skin cancer Tissue, 1:20-1:200; IF: MCF-7 Cells, 1:20-1:200; IP:A375 Cells, 1:200-1:2000
Type: Primary
Antigen: MLPH
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat