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Specifications
- Antibody type:Primary
- Antigen name:X-linked inhibitor of apoptosis
- Clonality:Polyclonal
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:XIAP
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:150 µL
- Western blot:Yes
- Antigen synonyms:IAP-like protein|HILP|API3|Baculoviral IAP repeat-containing protein 4|X-linked IAP|X-linked inhibitor of apoptosis protein|XIAP|IAP3|Inhibitor of apoptosis protein 3
- Storage buffer:PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
- Shipping temperature:Store at -20°C
- Immunogen:Recombinant Protein
- Purification:Protein A Purification
- Cat. no.:10097-170
- Supplier No.:10037-1-IG
Specifications
About this item
XIAP, also named as API3, BIRC4 and IAP3, belongs to the IAP family. It has E3 ubiquitin-protein ligase activity. It mediates the proteasomal degradation of target proteins, such as caspase-3, SMAC or AIFM1. XIAP is an inhibitor of caspase-3, -7 and -9. It mediates activation of MAP3K7/TAK1, leading to the activation of NF-kappa-B. XIAP is an apoptotic suppressor. It is ubiquitinated and degraded by the proteasome in apoptotic cells. The MW of XIAP is 45-56 kDa.
Western Blot: HepG2 Cells, 1:500-1:5000; IHC: Human pancreas cancer Tissue, 1:20-1:200; IF: MCF-7 Cells, 1:10-1:100
Type: Primary
Antigen: XIAP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat