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Specifications
- Antibody type:Primary
- Antigen name:Protein Tyrosine Phosphatase Receptor Type C
- Clonality:Monoclonal
- Clone:UCHL1
- Gene ID:5788
- Host:Mouse
- Isotype:IgG2a
- Neutralisation:Yes
- Reactivity:Chimpanzee,Human
- Antigen symbol:PTPRC
- Conjugation:Unconjugated
- Flow cytometry:Yes
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Size:100 µg
- Western blot:Yes
- Antigen synonyms:CD45R|B220|CD45|GP180|T200|L-CA|LY5|receptor type C|LCA|protein tyrosine phosphatase
- Storage temperature:Store undiluted at 2-8°C, protect from light, do not freeze.
- Tested applications:Immunofluorescence Microscopy
- Cat. no.:10051-694
- Supplier No.:70-0457-U100
Specifications
About this item
The UCHL1 antibody reacts with the human CD45 isoform known as CD45RO, a protein tyrosine phosphatase of 220 kDa. CD45 is one of the most abundant hematopoietic markers, and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). Various isoforms are generated and expressed in cell-specific patterns. With their broad cell distribution, CD45 isoforms are critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA and CD45RB.
The UCHL1 antibody is widely used as a marker for human CD45RO expression on thymocytes, activated memory T cells, monocytes, macrophages and granulocytes. The antibody is reported to be cross-reactive for Chimpanzee CD45RO.
Type: Primary
Antigen: PTPRC
Clonality: Monoclonal
Clone: UCHL1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: Human, Chimpanzee