About this item
The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB and CD45RO.
The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.
Type: Primary
Antigen: PTPRC
Clonality:
Clone: 30-F11
Conjugation: redFluor® 710
Epitope:
Host: Rat
Isotype: IgG2b
Reactivity: Mouse
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Specifications
- Catalog No:
- 10141-102
- 10141-104
- Antigen name:
- Protein Tyrosine Phosphatase Receptor Type C
- Protein Tyrosine Phosphatase Receptor Type C
- Antibody type:
- Primary
- Primary
- Clone:
- 30-F11
- 30-F11
- Host:
- Rat
- Rat
- Gene ID:
- 19264
- 19264
- Isotype:
- IgG2b
- IgG2b
- Neutralisation:
- Yes
- Yes