To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Specifications
- Protein/peptide type:Recombinant
- Source:E. coli
- Species:Human
- Size:0.01 mg
- Biological activity:Biological activity was determined by its ability to inhibit the proliferation of mouse MPC-11 cells. The expected ED50 is ≤ 2.0 ng/mL, corresponding to a specific activity of ≥ 5 x 105 units/mg. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
- Protein synonyms:Mothers against decapentaplegic homolog 2|hMAD-2|MAD homolog 2|hSMAD2|JV18-1|MADR2|MADH2|JV18
- Protein/peptide name:Activin A
- Purity:>97%
- Formulation:Lyophilized
- Cat. no.:10073-008
- Supplier No.:40-544
Specifications
About this item
Activin A is a TGF-β family member that exhibits a wide range of biological activities including regulation of cellular proliferation and differentiation, and promotion of neuronal survival. Elevated levels of Activin A in human colorectal tumors and in postmenopausal women have been implicated in colorectal and breast cancers, respectively. The biological activities of Activin A can be neutralized by inhibins and by the diffusible TGF-β antagonist, follistatin. Recombinant human Activin A is a 26.0 kDa disulfide-linked homodimer of two βA chains, each containing 116 amino acid residues.
Store in working aliquots at -20°C. Avoid freeze/thaw cycles.