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Specifications
- Antibody type:Primary
- Antigen name:low density lipoprotein receptor
- Clonality:Polyclonal
- Gene ID:P01130
- Host:Chicken
- Reactivity:Human,Rat,Mouse
- Antigen symbol:LDLR
- Conjugation:Unconjugated
- Size:0.05 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:LDLR
- Storage buffer:Phosphate-Buffered Saline. No preservatives added.
- Molecular weight:95.4 kDa (calculated)
- Storage temperature:LDLR antibody can be stored at 4 °C for short term (weeks). Long term storage should be at –20 °C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:29-205
- Purification:Antigen affinity-purified
- Cat. no.:10069-790
- Supplier No.:XW-7339
Specifications
About this item
Low density lipoprotein receptor. The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia.
LDL-R antibody can be used for the detection of LDL-R by Western blot, may also work for IHC and ICC.
Antigen affinity-purified
Phosphate-Buffered Saline. No preservatives added.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: LDLR
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Chicken
Isotype:
Reactivity: Human, Mouse, Rat