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Specifications
- Antibody type:Primary
- Antigen name:pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
- Clonality:Polyclonal
- Gene ID:P02775
- Host:Rabbit
- Neutralisation:Yes
- Reactivity:Human
- Antigen symbol:PPBP
- Conjugation:Unconjugated
- ELISA:Yes
- Size:0.1 mg
- Western blot:Yes
- Form:Lyophilized
- Antigen synonyms:PPBP
- Shipping temperature:RT
- Immunogen:Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hNAP-2 (human Neutrophil Activating Protein-2).
- Purification:Anti-hNAP-2 specific antibody was purified by affinity chromatography employing immobilized hNAP-2 matrix.
- Cat. no.:10097-544
- Supplier No.:XP-5244
Specifications
About this item
NAP2 is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.
Neutralization: To yield one-half maximal inhibition [ND50] oof the biological activity of hNAP-2 (50.00 ng/mL), a concentration of 1.75 - 3.0 µg/mL of this antibody is required. ELISA: To detect hNAP-2 by direct ELISA (using 100 µL/well antibody solution) a concentration of at least 0.5 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of 0.2 - 0.4 ng/well of recombinant hNAP-2. Sandwich: To detect hNAP-2 by sandwich ELISA (using 100 µL/well antibody solution) a concentration of 0.5 - 2.0 µg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our Biotinylated Anti-Human NAP-2 (XP-5244Bt) as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant hNAP-2. Western Blot: To detect hNAP-2 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant hNAP-2 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
Anti-hNAP-2 specific antibody was purified by affinity chromatography employing immobilized hNAP-2 matrix.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: PPBP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human