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Specifications
- Antibody type:Primary
- Antigen name:amyloid beta (A4) precursor protein
- Clonality:Polyclonal
- Gene ID:P05067
- Host:Rabbit
- Reactivity:Human,Rat,Mouse
- Antigen symbol:APP
- Conjugation:Unconjugated
- ImmunoFluorescence:Yes
- Size:0.1 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:APP
- Storage buffer:Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- Molecular weight:100 - 140 kDa
- Storage temperature:Store antibody at –20 °C for up to one year.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:APP (Ab-668) antibody was raised against a peptide sequence around aa.666~670 (A-V-T-P-E ) derived from Human APP.
- Purification:Antibodies were purified by affinity-chromatography using epitope-specific peptide.
- Cat. no.:10070-382
- Supplier No.:79-581
Specifications
About this item
APP encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
- Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: APP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat