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Specifications
- Antibody type:Primary
- Antigen name:coiled-coil-helix-coiled-coil-helix domain containing 6
- Clonality:Polyclonal
- Gene ID:Q9BRQ6
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:CHCHD6
- Conjugation:Unconjugated
- ELISA:Yes
- Size:0.1 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:CHCHD6
- Storage buffer:CHCHD6 Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:Predicted: 26 kDa
- Storage temperature:CHCHD6 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:Rabbit polyclonal CHCHD6 antibody was raised against a 17 amino acid peptide near the amino terminus of human CHCHD6. The immunogen is located within amino acids 20 - 70 of CHCHD6.
- Purification:CHCHD6 Antibody is affinity chromatography purified via peptide column.
- Cat. no.:10062-518
- Supplier No.:7133
Specifications
About this item
CHCHD6 Antibody: CHCHD6 is a member of a family of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain and has been observed in a complex with the mitochondrial proteins mitofilin, SAM50, metaxins 1 and 2, and CHCHD3. CHCHD6 knockdown causes severe defects in mitochondrial cristae morphology as well as reductions in cell growth, ATP production and oxygen consumption. This decrease of CHCHD6 also led to a reduction in mitofilin protein levels, while a knockdown of mitofilin resulted in a reduced level of CHCHD6, suggesting coordinate regulation between these two proteins. CHCHD6 knockdown in human cancer cells enhances their sensitivity to genotoxic anticancer drugs, suggesting that CHCHD6 may be a potential therapeutic anti-tumor target.
CHCHD6 antibody can be used for detection of CHCHD6 by Western blot at 1 - 2 ?g/mL.
CHCHD6 Antibody is affinity chromatography purified via peptide column.
CHCHD6 Antibody is supplied in PBS containing 0.02% sodium azide.
CHCHD6 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Type: Primary
Antigen: CHCHD6
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human