To order chemicals, medical devices, or other restricted products please provide ID that includes your business name & shipping address via email [email protected] or fax 484.881.5997 referencing your VWR account number. Acceptable forms of ID are:
- • State issued document with your organization's Federal Tax ID Number
- • State issued document with your organization's Resale Tax ID Number
- • City or County issued Business License
- • State Department of Health Services License
- • Any other ID issued by the State that includes the business name & address
* ATTN: California Customers may require additional documentation as part of the CA Health & Safety Code. Products that fall under this regulation will be placed on a mandatory 21-day hold after documentation is received. VWR will not lift restrictions for residential shipping addresses.
Specifications
- Antibody type:Primary
- Antigen name:solute carrier family 6 (neurotransmitter transporter), member 13
- Clonality:Polyclonal
- Gene ID:P31646
- Host:Rabbit
- Reactivity:Rat,Mouse
- Antigen symbol:Slc6a13
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- Size:0.1 mL
- Form:Liquid
- Antigen synonyms:Slc6a13
- Storage buffer:100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
- Molecular weight:82
- Storage temperature:GAT-2 antibody can be stored at –20 °C and is stable at –20 °C for at least 1 year.
- Shipping temperature:4 °C
- Immunogen:Peptide corresponding to amino acid residues from the C-terminal region of rat GAT-2.
- Purification:Affinity Purified
- Cat. no.:10075-496
- Supplier No.:50-216
Specifications
About this item
Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl− channel associated with the GABAA receptor (GABAA-R) subtype. GABA plasma membrane transporters (GATs) influence synaptic neurotransmission by high-affinity uptake and release of GABA. To date, four distinct GABA transporters have been identified: GAT-1, GAT-2, GAT-3, and BGT-1. GAT-2 is found in a wide range of neuronal and non-neuronal cells including dendrites and axon terminals as well as epithelial cells and cells forming the pia and arachnoid complex (Conti et al., 1999).
The antibody has been directly tested for reactivity in immunohistochemistry in rat cortex and retinal sections. It is anticipated that the antibody will also work in mouse sections based on the fact that this species has 100% homology with the amino acid sequence used as antigen.
Affinity Purified
100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: Slc6a13
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Mouse, Rat