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Specifications
- Antibody type:Primary
- Antigen name:glutamate receptor, ionotropic, N-methyl D-aspartate 2A
- Clonality:Polyclonal
- Gene ID:Q00959
- Host:Rabbit
- Reactivity:Human,Rat,Mouse
- Antigen symbol:Grin2a
- Conjugation:Unconjugated
- Size:.05 mL
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:Grin2a
- Molecular weight:180
- Storage temperature:NMDA antibody can be stored at –20 °C and is stable at –20 °C for at least 1 year.
- Shipping temperature:4 °C
- Immunogen:Fusion protein from the C-terminus region of the NR2A subunit of rat NMDA receptor.
- Purification:Neat Serum
- Cat. no.:10073-256
- Supplier No.:50-180
Specifications
About this item
The NMDA receptor (NMDAR) plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer’s, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002; Wenthold et al., 2003; Carroll and Zukin, 2002). The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS (Lovinger et al., 1989; Alvestad et al., 2003; Snell et al., 1996). The NMDAR is also potentiated by protein phosphorylation (Lu et al., 1999). The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.
The antibody has been directly tested for reactivity in Western blots with human, mouse and rat tissue.
Neat Serum
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: Grin2a
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat