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Specifications
- Antibody type:Primary
- Antigen name:tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
- Clonality:Polyclonal
- Gene ID:P35213
- Host:Rabbit
- Reactivity:Zebrafish,Xenopus,Chicken,Human,Bovine,Dog,Rat,Mouse
- Antigen symbol:Ywhab
- Conjugation:Unconjugated
- Size:0.1 mL
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:Ywhab
- Storage buffer:100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
- Molecular weight:29
- Storage temperature:14-3-3 antibody can be stored at –20 °C and is stable at –20 °C for at least 1 year.
- Shipping temperature:4 °C
- Immunogen:Peptide corresponding to amino acid residues from the C-terminal region of 14-3-3 protein, conjugated to keyhole limpet hemocyanin (KLH).
- Purification:Affinity Purified
- Cat. no.:10075-470
- Supplier No.:50-178
Specifications
About this item
14-3-3 proteins are a family of highly conserved proteins that appear to have multiple roles in cell signaling (Bridges and Moorhead, 2005). The proteins are abundantly expressed in the brain and have been detected in the cerebrospinal fluid of patients with different neurological disorders (Berg et al., 2003). 14-3-3 proteins bind protein ligands that are typically phosphorylated on serine or threonine residues and regulate the functions of these binding partners by a number of different mechanisms (Silhan et al., 2004; Dougherty and Morrison, 2004). The 14-3-3 proteins affect a diverse array of cellular processes including the cell cycle and transcription, signal transduction and intracellular trafficking.
The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with bovine, canine, chicken, human, mouse, non-human primates, Xenopus and zebra fish based on the fact that these species have 100% homology with the amino acid sequence used as antigen.
Affinity Purified
100 uL in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per mL BSA and 50% glycerol.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: Ywhab
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat, Dog, Zebrafish, Bovine, Chcicken, Xenopus