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Specifications
- Antibody type:Primary
- Antigen name:Bloom syndrome, RecQ helicase-like
- Clonality:Polyclonal
- Gene ID:P54132
- Host:Rabbit
- Isotype:IgG
- Reactivity:Sheep,Non-human primates,Human,Bovine
- Antigen symbol:BLM
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- Size:0.05 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:BLM
- Modification:Ser 186
- Shipping temperature:4 °C
- Immunogen:A synthetic peptide surrounding amino acid S186.
- Purification:Affinity Purified
- Cat. no.:10068-244
- Supplier No.:39-857
Specifications
About this item
The Bloom syndrome gene product is a member of the RecQ helicase protein family. The protein contains 1417 amino acids; including one ATP binding site, one DEAH box, and two putative nuclear localization signals, as well as phosphorylation sites. BLS protein is known to associate and be phosphorylated by the ATR (ataxia telangiectasia, rad3+) protein, in response to genetic stress. The Bloom's syndrome gene product is thought to play a role in the etiology of two major human health problems, each of which is a very common complication of Bloom's syndrome, namely cancer and diabetes.
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Affinity Purified
Type: Primary
Antigen: BLM
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Non-Human Primate