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Specifications
- Antibody type:Primary
- Antigen name:leptin
- Clonality:Monoclonal
- Clone:G1_4B6.3
- Gene ID:P41159
- Host:Mouse
- Neutralisation:Yes
- Reactivity:Human
- Antigen symbol:LEP
- Conjugation:Unconjugated
- ELISA:Yes
- Size:0.5 mg
- Western blot:Yes
- Form:Lyophilized
- Antigen synonyms:LEP
- Shipping temperature:RT
- Immunogen:Leptin antibody is produced in BALB/c mice using highly pure (>98%) recombinant human Leptin as the immunizing antigen.
- Purification:This IgG1K antibody was purified from cell culture by Protein A affinity chromatography.
- Cat. no.:10097-926
- Supplier No.:38-235
Specifications
About this item
Leptin plays a critical role in the regulation of body weight by inhibiting food intake and stimulating energy expenditure. Defects in Leptin production cause severe hereditary obesity in rodents and humans. In addition to its effects on body weight, leptin has a variety of other functions, including the regulation of hematopoiesis, angiogenesis, wound healing, and the immune and inflammatory response. The Leptin gene is the human homolog of the gene (ob) mutant in the mouse 'obese' phenotype.
Was product number XP-5712-M
Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of mIL-2 (1.0 ng/mL), a concentration of 10.0-14.0 µg/mL of this antibody is required. ELISA: In a sandwich ELISA (assuming 100 µL/well), a concentration of 4.0-8.0 µg/mL of this antibody will detect at least 32 pg/mL of recombinant murine IL-2 when used with our biotinylated antigen affinity purified anti-murine IL-2 (XP-5183Bt) as the detection antibody at a concentration of at least 1.0-2.0 µg/mL. Western Blot: To detect mIL-2 by Western Blot analysis this antibody can be used at a concentration of 2.0-4.0 µg/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant mIL-2 is 1.0-2.0 ng/lane, under reducing conditions and 0.2-0.4 ng/lane, under non-reducing conditions.
This IgG1K antibody was purified from cell culture by Protein A affinity chromatography.
The reconstituted antibody can temporarily be stored at 2-8°C. Long term storage at -20°C or below. Avoid repeated freeze-thaw cycles.
Type: Primary
Antigen: LEP
Clonality: Monoclonal
Clone: G1_4B6.3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype:
Reactivity: Human