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Specifications
- Antibody type:Primary
- Antigen name:desmin
- Clonality:Monoclonal
- Clone:10H7D2
- Gene ID:P17661
- Host:Mouse
- Isotype:IgG1
- Reactivity:Human
- Antigen symbol:DES
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- Size:0.1 mg
- Western blot:Yes
- Antigen synonyms:DES
- Storage buffer:Purified antibody in PBS containing 0.03% sodium azide.
- Storage temperature:Desmin monoclonal antibody can be stored at –20 °C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Shipping temperature:4 °C
- Immunogen:Ni-NTA purified truncated recombinant Desmin expressed in E. Coli strain BL21 (DE3).
- Cat. no.:10073-230
- Supplier No.:32-145
Specifications
About this item
Desmin (DES), with 470-amino acid protein (about 52 kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.
Western Blot:1:1,000 - 1:2,000
IHC(P):1:1,000 - 1:2,000
IHC(F):1:1,000 - 1:2,000
ELISA:Propose dilution 1:10,000.
Determining optimal working dilutions by titration test.
Purified antibody in PBS containing 0.03% sodium azide
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: DES
Clonality: Monoclonal
Clone: 10H7D2
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human