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Specifications
- Antibody type:Primary
- Antigen name:sodium channel, voltage-gated, type V, alpha subunit
- Clonality:Polyclonal
- Gene ID:Q8IZC9
- Host:Rabbit
- Reactivity:Zebrafish,Human,Dog,Rat,Mouse
- Antigen symbol:SCN5A
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- Size:100 ul
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:SCN5A
- Storage buffer:Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Molecular weight:222 kDa, 227 kDa, 36 kDa
- Storage temperature:For short periods of storage (days) store at 4 °C. For longer periods of storage, store SCN5A antibody at –20 °C. As with any antibody avoid repeat freeze-thaw cycles.
- Shipping temperature:4 °C
- Immunogen:Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SCN5A.
- Purification:Antibody is purified by peptide affinity chromatography method.
- Cat. no.:10101-242
- Supplier No.:28-312
Specifications
About this item
SCN5A is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. The protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram.The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. The encoded protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in two transcript variants encoding separate isoforms which differ by a single amino acid. Mutation nomenclature has been assigned with respect to the longer isoform.
SCN5A antibody can be used for detection of SCN5A by ELISA at 1:312500. SCN5A antibody can be used for detection of SCN5A by western blot at 0.25 ?g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Antibody is purified by peptide affinity chromatography method.
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: SCN5A
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat, Dog, Zebrafish