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Specifications
- Antibody type:Primary
- Antigen name:poly (ADP-ribose) polymerase family, member 11
- Clonality:Polyclonal
- Gene ID:P09874
- Host:Rabbit
- Reactivity:Human,Dog,Rat,Mouse
- Antigen symbol:PARP11
- Conjugation:Unconjugated
- ELISA:Yes
- Size:100 ul
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:PARP11
- Storage buffer:Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
- Molecular weight:113 kDa
- Storage temperature:For short periods of storage (days) store at 4 °C. For longer periods of storage, store PARP1 antibody at –20 °C. As with any antibody avoid repeat freeze-thaw cycles.
- Shipping temperature:4 °C
- Immunogen:Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARP1.
- Purification:Antibody is purified by protein A chromatography method.
- Cat. no.:10105-742
- Supplier No.:27-939
Specifications
About this item
PARP1 encodes a chromatin-associated enzyme, poly (ADP-ribosyl)transferase, which modifies various nuclear proteins by poly (ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. PARP1 can be cleaved resulting in fragements of 29 and 85 kDa.
PARP1 antibody can be used for detection of PARP1 by ELISA at 1:62500. PARP1 antibody can be used for detection of PARP1 by western blot at 5.0 ?g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Antibody is purified by protein A chromatography method.
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Type: Primary
Antigen: PARP11
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human, Mouse, Rat, Dog