The SpectraMax® M2 and M2e Multimode Microplate Readers provide two detection modes in one platform and offer the added functionality of bottom-read fluorescence for cell-based assays.

• Two detection modes
• PathCheck® PathLength measurement technology
• Eliminate standard curves

SpectraMax® M2 and M2e Microplate Readers are the standard for UV/visible multimode reader absorbance, providing ultrafast and full spectral range detection for cuvettes and 6-, 12-, 24-, 48-, 96-, and 384-well microplates

For fluorescence intensity assays, the SpectraMax® M2 and M2e units feature an optical design that provides the highest level of flexibility. Users can select from top- or bottom-read modes for improved sensitivity for solution and cell-based assays (M2e only). Assays can be better optimized by scanning across a range of wavelengths in increments as small as 1nm. Up to 4 wavelength pairs can be read in one protocol for endpoint and kinetic measurements, allowing for fast setup of FRET assays.

Using patented PathCheck® PathLength Measurement Technology, these units transform each well in a microplate into a fixed optical pathlength cuvette. They can eliminate standard curves by allowing the calculation of concentrations directly from the absorbance with a known extinction coefficient, as exemplified with nucleic acid and protein quantitation.