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Specifications
- Antibody type:Primary
- Antigen name:dispatched homolog 2 (Drosophila)
- Clonality:Polyclonal
- Gene ID:A7MBM2
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:DISP2
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- Size:0.1 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:DISP2
- Storage buffer:DISP2 Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage temperature:DISP2 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:DISP2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DISP2. The immunogen is located within amino acids 110 - 160 of DISP2.
- Tested applications:E, IHC
- Purification:DISP2 Antibody is affinity chromatography purified via peptide column.
- Cat. no.:89416-800
- Supplier No.:4893
Specifications
About this item
DISP2 Antibody: DISP2 is the second of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored Hedgehog from producing cells. Hedgehog is a major player in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis and the DISP proteins have been implicated in these pathways. Recently, it has been shown that DISP2 is translationally regulated by the microRNA miR-214 in zebrafish. Expression of this miRNA decreased DISP2 promoter activity in vitro and its overexpression in zebrafish resulted in a phenotype identical to that observed by DISP2 mutants.
Type: Primary
Antigen: DISP2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human