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Anti-KPNA1 Rabbit Polyclonal Antibody
Anti-KPNA1 Rabbit Polyclonal Antibody
Catalog #: 89417-608
Supplier:  Prosci
Antibody KPNA1 0.1MG
Anti-KPNA1 Rabbit Polyclonal Antibody
Catalog #: 89417-608
Supplier:  Prosci
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Specifications

  • Antibody type:
    Primary
  • Antigen name:
    karyopherin alpha 1 (importin alpha 5)
  • Clonality:
    Polyclonal
  • Gene ID:
    P52294
  • Host:
    Rabbit
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Antigen symbol:
    KPNA1
  • Conjugation:
    Unconjugated
  • ELISA:
    Yes
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Size:
    0.1 mg
  • Western blot:
    Yes
  • Form:
    Liquid
  • Antigen synonyms:
    KPNA1
  • Storage buffer:
    KPNA1 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Storage temperature:
    KPNA1 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Concentration:
    1 mg/mL
  • Shipping temperature:
    4 °C
  • Immunogen:
    KPNA1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human KPNA1. The immunogen is located within amino acids 30 - 80 of KPNA1.
  • Tested applications:
    Immunocytochemistry
  • Purification:
    KPNA1 Antibody is affinity chromatography purified via peptide column.
  • Cat. no.:
    89417-608
  • Supplier No.:
    5981

Specifications

About this item

KPNA1 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA1, also known as importin alpha 5, is the alpha subunit of karyopherin, which forms a complex with importin subunit beta-1 and functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. It is ubiquitously expressed and polyubiquitinated in the presence of RAG1. KPNA1 interacts with various virus nucleoproteins, including those of Ebola and influenza.

Type: Primary
Antigen: KPNA1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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