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Anti-APC3 Rabbit Polyclonal Antibody
Anti-APC3 Rabbit Polyclonal Antibody
Catalog #: 89417-428
Supplier:  Prosci
Antibody APC3 0.1MG
Anti-APC3 Rabbit Polyclonal Antibody
Catalog #: 89417-428
Supplier:  Prosci
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Specifications

  • Antibody type:
    Primary
  • Antigen name:
    cell division cycle 27 homolog (S. cerevisiae)
  • Clonality:
    Polyclonal
  • Gene ID:
    P30260
  • Host:
    Rabbit
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Antigen symbol:
    CDC27
  • Conjugation:
    Unconjugated
  • ELISA:
    Yes
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Size:
    0.1 mg
  • Western blot:
    Yes
  • Form:
    Liquid
  • Antigen synonyms:
    CDC27
  • Storage buffer:
    APC3 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Storage temperature:
    APC3 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Concentration:
    1 mg/mL
  • Shipping temperature:
    4 °C
  • Immunogen:
    APC3 antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human APC3. The immunogen is located within the last 50 amino acids of APC3.
  • Tested applications:
    E, WB, IHC, IF
  • Purification:
    APC3 Antibody is affinity chromatography purified via peptide column.
  • Cat. no.:
    89417-428
  • Supplier No.:
    5723

Specifications

About this item

APC3 Antibody: Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC3, also known as CDC27, a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), is a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. APC3 contains a tetratricopeptide repeat (TPR) region and interacts with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1.

Type: Primary
Antigen: CDC27
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat

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