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Specifications
- Antibody type:Primary
- Antigen name:Rho guanine nucleotide exchange factor (GEF) 17
- Clonality:Polyclonal
- Gene ID:Q96PE2
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:ARHGEF17
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:0.1 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:ARHGEF17
- Storage buffer:TEM4 Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:Predicted: 220 kDa Observed: 200 kDa
- Storage temperature:TEM4 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:TEM4 antibody was raised against a 18 amino acid synthetic peptide near the center of human TEM4. The immunogen is located within amino acids 910 - 960 of TEM4.
- Tested applications:E, WB, IHC, IF
- Purification:TEM4 Antibody is affinity chromatography purified via peptide column.
- Cat. no.:89416-400
- Supplier No.:4367
Specifications
About this item
TEM4 Antibody: Rho GTPases, which are activated by specific guanine-nucleotide exchange factors (GEFs), play pivotal roles in several cellular functions. TEM4, encoding a protein containing 1510 amino acids, contains a RhoGEF-specific Dbl homology (DH) domain but lacks their typical pleckstrin homology domain. TEM4 is a Rho-specific GEF with novel structural and regulatory properties and predominant expression in the heart. It couples tyrosine kinase signals with the activation of the rho/rac GTPases, thus leading to cell differentiation and/or proliferation. Elevated levels of TEM4, TEM5, TEM6, TEM7 and TEM7R were also raised in breast cancer tissues. TEM4 could also prove to be useful targets therapeutically.
Type: Primary
Antigen: ARHGEF17
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human