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Specifications
- Antibody type:Primary
- Antigen name:DEXH (Asp-Glu-X-His) box polypeptide 58
- Clonality:Polyclonal
- Gene ID:Q96C10
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:DHX58
- Conjugation:Unconjugated
- ELISA:Yes
- Size:0.1 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:DHX58
- Storage buffer:LGP2 Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage temperature:LGP2 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:LGP2 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human LGP2. The immunogen is located within amino acids 90 - 140 of LGP2.
- Tested applications:E, WB
- Purification:LGP2 Antibody is affinity chromatography purified via peptide column.
- Cat. no.:89416-388
- Supplier No.:4353
Specifications
About this item
LGP2 Antibody: Anti-viral innate immune responses are triggered by pathogen-associated molecular patters (such as the accumulation of intracellular nucleic acids resulting from virus infections) and represent the first line of defense against numerous infectious organisms. The Toll-like receptors (TLR) 3, 7, 8, and 9 are expressed in immune cells and function as transmembrane pattern recognition receptors to detect foreign nucleic acids. Other proteins that play similar roles, such as RIG-1 and MDA5 are members of a CARD-helicase family and are expressed in the cytoplasm. A third protein, LGP2, is similar to RIG-1 and MDA5, except for lacking a homologous CARD domain. It is thought to act as an element of negative-feedback regulation of intracellular antiviral signaling. At least four isoforms of LGP2 are known to exist.
Type: Primary
Antigen: DHX58
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat