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Anti-PDL2 Rabbit Polyclonal Antibody
  89416-220
 :  Prosci
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Anti-PDL2 Rabbit Polyclonal Antibody
  89416-220
 :  Prosci
 :  4063
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  • Antibody type:
    Primary
  • Antigen name:
    programmed cell death 1 ligand 2
  • Antigen symbol:
    PDCD1LG2
  • Clonality:
    Polyclonal
  • Conjugation:
    Unconjugated
  • ELISA:
    Yes
  • Host:
    Rabbit
  • ImmunoChemistry:
    Yes
  • ImmunoFluorescence:
    Yes
  • Isotype:
    IgG
  • Reactivity:
    Human,
    Rat,
    Mouse
  • Western blot:
    Yes
  • Size:
    0.1 mg
  • Environmentally Preferable:
  • Form:
    Liquid
  • Gene ID:
    Q9BQ51
  • Antigen synonyms:
    PDCD1LG2
  • Storage buffer:
    PD-L2 Antibody is supplied in PBS containing 0.02% sodium azide.
  • Molecular weight:
    Predicted: 30 kDa Observed: 32 kDa
  • Storage temperature:
    PD-L2 antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Concentration:
    1 mg/mL
  • Shipping temperature:
    4 °C
  • Immunogen:
    PD-L2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human PD-L2. The immunogen is located within amino acids 140 - 190 of PD-L2.
  • Tested applications:
    E, WB, IHC, IF
  • Purification:
    PD-L2 Antibody is affinity chromatography purified via peptide column.
  • Cat. no.:
    89416-220
  • Supplier No.:
    4063

 

 

PDL-2 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by co gnate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2, both of which are thought act as a negative regulator of T cell activation. However, it has been suggested that PDL-2 can act to stimulate an immunogenic response through and alternative receptor from PD-1. At least three isoforms of PDL-2 are known to exist; this antibody is specific to the largest isoform. PDL-2 antibody has no cross-reactivity to PDL-2.

Type: Primary
Antigen: PDCD1LG2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat