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Specifications
- Antibody type:Primary
- Antigen name:tumor necrosis factor (ligand) superfamily, member 11
- Clonality:Polyclonal
- Gene ID:O14788
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human,Rat,Mouse
- Antigen symbol:TNFSF11
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- Size:0.1 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:TNFSF11
- Storage buffer:sRANK Ligand Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:35 kDa
- Storage temperature:sRANK Ligand antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:sRANK-L antibody was raised against a 14 amino acid synthetic peptide from near the center of human sRANK-L. The immunogen is located within amino acids 140 - 190 of sRANK Ligand.
- Tested applications:E, WB, IHC
- Purification:sRANK Ligand Antibody is affinity chromatography purified via peptide column.
- Cat. no.:89416-140
- Supplier No.:3963
Specifications
About this item
sRANK Ligand Antibody: The receptor activator of NF-kappa B ligand (RANK-L) is a recently discovered member of the TNF-ligand family involved in the regulation of the T cell-dependent immune response, lymph node organogenesis and bone formation. RANK-L exists as both a normal, transmembrane form and a truncated, soluble form (sRANK-L), both of which can stimulate the receptor. Activation of T cells, such as by treatment with interleukin-7, induces RANK-L production and leads to an increase of osteoclast formation and bone loss. Finally, sRANK-L can activate the antiapoptotic kinase Akt through a signaling complex involving Src kinase and TRAF6, suggesting sRANK-L may also play a role in regulating apoptosis. This antibody will recognize both the soluble form and the uncleaved transmembrane form of RANK-L.
Type: Primary
Antigen: TNFSF11
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat