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Specifications
- Antibody type:Primary
- Antigen name:tripartite motif-containing 5
- Clonality:Polyclonal
- Gene ID:Q9C035
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:TRIM5
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:0.1 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:TRIM5
- Storage buffer:TRIM5 alpha Antibody is supplied in PBS containing 0.02% sodium azide.
- Storage temperature:TRIM5 alpha antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Concentration:1 mg/mL
- Shipping temperature:4 °C
- Immunogen:TRIM5 alpha antibody was raised against a synthetic peptide corresponding to amino acids near the mid-region of human TRIM5 alpha. The immunogen is located within amino acids 370 - 420 of TRIM5 alpha.
- Tested applications:E, WB, IHC, IF
- Purification:TRIM5 alpha Antibody is affinity chromatography purified via peptide column.
- Cat. no.:89415-650
- Supplier No.:3247
Specifications
About this item
TRIM5 alpha Antibody: TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. Expression of TRIM5 alpha variants from humans, rhesus monkeys, and African green monkeys enabled resistance to infection by various retroviruses including HIV-1, albeit at differing efficiencies. All TRIM5 alpha variants could inhibit at least two different retroviruses, but not from those viruses isolated from the same species, suggesting that TRIM5 alpha acts as a natural barrier to cross-species retrovirus transmission.
Type: Primary
Antigen: TRIM5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human