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Specifications
- Antibody type:Primary
- Antigen name:inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
- Clonality:Polyclonal
- Gene ID:O14920
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:IKBKB
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- ImmunoFluorescence:Yes
- Size:0.1 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:IKBKB
- Storage buffer:IKK beta Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:87 kDa
- Storage temperature:IKK beta antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Shipping temperature:4 °C
- Immunogen:IKK beta antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human IKK beta (Genbank accession NoO14920), which differs from corresponding murine sequence by one amino acid. The immunogen is located within amino acids 650 - 700 of IKK beta.
- Tested applications:Immunocytochemistry
- Purification:IKK beta Antibody is affinity chromatography purified via peptide column.
- Cat. no.:89415-324
- Supplier No.:2121
Specifications
About this item
IKK beta Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF alpha , and bacteria product LPS. NF-kappa B is associated with I kappa B proteins in the cell cytoplasm, which inhibit NF-kappa B activity. The long-sought I kappa B kinase (IKK), which phosphorylates I kappa B, and mediates I kappa B degradation and NF-kappa B activation, was recently identified by several laboratories. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta ). IKK alpha and IKK beta interact with each other and both are essential for NF-kappa B activation. IKK beta phosphorylates both I kappa B-alpha and I kappa B-beta. IKK beta is expressed in variety of human tissues.
Type: Primary
Antigen: IKBKB
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human