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Specifications
- Antibody type:Primary
- Antigen name:conserved helix-loop-helix ubiquitous kinase
- Clonality:Polyclonal
- Gene ID:O15111
- Host:Rabbit
- Isotype:IgG
- Reactivity:Human
- Antigen symbol:CHUK
- Conjugation:Unconjugated
- ELISA:Yes
- ImmunoChemistry:Yes
- Size:0.1 mg
- Western blot:Yes
- Form:Liquid
- Antigen synonyms:CHUK
- Storage buffer:IKK alpha Antibody is supplied in PBS containing 0.02% sodium azide.
- Molecular weight:Observed: 87 kDa
- Storage temperature:IKK alpha antibody can be stored at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Shipping temperature:4 °C
- Immunogen:IKK alpha antibody was raised against a 17 amino acid peptide near the carboxy terminus of human IKK alpha. The immunogen is located within amino acids 640 - 690 of IKK alpha.
- Tested applications:Immunocytochemistry
- Purification:IKK alpha Antibody is affinity chromatography purified via peptide column.
- Cat. no.:89415-322
- Supplier No.:2117
Specifications
About this item
IKK alpha Antibody: Nuclear factor kappa B (NF-kappa B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-kappa B mediates the expression of a great variety of genes in response to extracellular stimuli including IL-1, TNF alpha and bacteria product LPS. NF-kappa B is associated with I kappa B proteins in the cell cytoplasm, which inhibit NF-kappa B activity. The long-sought I kappa B kinase (IKK), which phosphorylates I kappa B, and mediates I kappa B degradation and NF-kappa B activation, was recently identified by several laboratories. IKK is a serine protein kinase, and the IKK complex contains alpha and beta subunits (IKK alpha and IKK beta ). IKK alpha and IKK beta interact with each other and both are essential for the NF-kappa B activation. IKK alpha specifically phosphorylates I kappa B-alpha. IKK alpha is expressed in a variety of human tissues.
Type: Primary
Antigen: CHUK
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human