Butyl Sepharose™ HP media is particularly well suited for intermediate purification and polishing steps providing high resolution due to the small particle size.

• Aliphatic HIC medium designed for intermediate purification and polishing steps
• BioProcess medium supported for industrial applications
• Selectivity similar to Butyl Sepharose 4 Fast Flow but higher resolution due to the smaller 34 µm bead size
• Relatively high ligand density for high dynamic binding capacity even at relatively low salt concentrations
• The hydrophilic nature of the base matrix ensures low levels of non-specific binding

Butyl Sepharose High Performance is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, Butyl Sepharose High Performance meets industrial demands with security of supply and comprehensive technical and regulatory support.

Butyl Sepharose High Performance is based on highly crosslinked, 34-µm agarose beads modified with aliphatic butyl groups via uncharged, chemically stable ether linkages. It is a truly hydrophobic medium displaying a minimum of ionic interactions. Butyl Sepharose High Performance media is particularly well suited for intermediate purification and polishing steps providing high resolution due to the small particle size.