Butyl Sepharose 4 Fast Flow is part of the Sepharose Fast Flow HIC platform, which has been an industrial standard for HIC chromatography during recent decades

• Standard aliphatic HIC media based on Sepharose Fast Flow base matrix derivatized via uncharged, chemically-stable ether linkages
• Optimized for the separation of larger proteins in capture and intermediate purification steps
• The hydrophilic nature of the base matrix ensures low levels of non-specific binding

BioProcess medium supported for industrial applications and well-established in approved processes. Butyl Sepharose 4 Fast Flow is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, Butyl Sepharose 4 Fast Flow meets industrial demands with security of supply and comprehensive technical and regulatory support.

Butyl Sepharose 4 Fast Flow is based on cross-linked 4% agarose. The aliphatic ligand is immobilized to the base matrix with an ether linkage. The ligand contains no charged groups, making true hydrophobic interaction chromatography possible, without interfering ionic effects.