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Specifications
- Protein/peptide type:Recombinant
- Source:Insect cells (Sf9)
- Species:Human
- Size:10 µg
- Tag sequence:HIS Tag
- Biological activity:1140 pmol/min/µg (9ng NEP were used to cleave 10µM Mca-RPPGFSAFK(Dnp)-OH (Fluorogenic Substrate) (Prod. No. BML-P227) at 37°C in 50mM TRIS, pH 9.0)
- Protein/peptide name:Neprilysin
- Purity:>95% (SDS-PAGE)
- Concentration:0.23 μg/μl
- Formulation:Liquid. In 50mM TRIS, pH 8.0. containing 300mM sodium chloride and 20% glycerol.
- Purification:Purified as the glycosylated soluble form.
- Cat. no.:89164-470
- Supplier No.:SE532-0010
Specifications
About this item
Highly active
Produced in Sf9 cells.
Neprilysin is a glycosylated zinc endopeptidase whose physiological targets include bradykinin, glucagon, GLP-1, and neuropeptides. Preferential cleavage of polypeptides between hydrophobic residues, particularly with Phe or Tyr at P1.