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Specifications
- Size:50 µg
- Protein/peptide name:MALP-2
- Concentration:0.1mg/ml
- Formulation:Liquid. Sterile solution in PBS containing 2.5% (v/v) 2-propanol, 25mM n-octyl-β-D-glucopyranoside and 1% (wt/v) human serum albumin.
- Cat. no.:89143-590
- Supplier No.:162-027-C050
Specifications
About this item
TLR activator
MALP-2 was originally isolated from Mycoplasma fermentans. This MALP-2 corresponds to the originally isolated isomer, which expresses potent endotoxin-like activity and approaches in certain experimental systems the toxicity of LPS. For description of the stereochemistry of MALP-2 please refer to M. Morr, et al. Eur. J. Immunol. 32, 3337 (2002). The importance of the stereochemistry of the central carbon atom of the diacylglycerol group has been described in the K.M. Omueti, et al. paper (2005), see below. MALP-2 signaling, unlike that of LPS, is not transduced via TLR4, but is induced via TLR2 and TLR6 signaling. For more information about MALP-2 see www.malp-research.de.