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Specifications
- Antibody type:Primary
- Antigen name:Nitrotyrosine
- Clonality:Monoclonal
- Host:Mouse
- Isotype:IgG1
- Reactivity:Human
- Antigen symbol:Nitro-Tyr
- ELISA:Yes
- Size:100 µg
- Western blot:Yes
- Form:Lyophilized from 1ml of 2x PBS containing 0.09% sodium azide, PEG, and sucrose.
- Purification:Thiophilic adsorption and size exclusion chromatography purified
- Cat. no.:89141-426
- Supplier No.:905-763-100
Specifications
About this item
The enzymatic conversion of arginine to citrulline by nitric oxide synthase (NO Synthase) leads to the formation of nitric oxide (NO). Peroxynitrite is formed following reaction of NO with superoxide, producing a potent oxidant that reacts with a variety of biological molecules, including tyrosine residues in proteins. Tyrosine nitration can inactivate enzymes and receptors that depend on tyrosine residues for their activity. Nitration prevents phosphorylation of tyrosine residues important for signal transduction.
- For ELISA, Flow Cytometry, Western Blot
Recognizes human, mouse, rat and dog Nitrotyrosine.
Reconstitute with 1ml water (15 minutes at room temperature).
Type: Primary
Antigen: NITROTYROSINE
Clonality: Monoclonal
Clone:
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity: Human