Ac-Tyr-Val-Ala-Asp-chloromethylketone

About this item

See also the Asp derivatives N-1425 and N-1430, and Z-YVAD-FMK (N-1595).

Cell-permeable, irreversible inhibitor of caspase-1 (ICE). N.Rouquet et al. showed that Ac-YVAD-CMK is a potent therapeutic agent against in vivo liver apoptosis in mice.

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