Peptide and amino acid chloromethyl ketones (CMK's) are irreversible inhibitors of cysteine proteases, but they also react with serine proteases. For our amino acid CMK's (e.g. TPCK, TLCK) see the corresponding product family in the 'Amino acid' section.

AAF-CMK, serine protease inhibitor. For tripeptidyl peptidase I (E.C. 3.4.14.9) a Ki value of 63 nM has been reported.

AAF-CMK, serine protease inhibitor. For tripeptidyl peptidase I (E.C. 3.4.14.9) a Ki value of 63 nM has been reported.