Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH Trifluoroacetate

Catalog #: M-2195.0001BA

Supplier: Bachem Americas

CAS Number:

Catalog #: M-2195.0001BA

Supplier: Bachem Americas

CAS Number:

Specifications

CAS No.:
189696-01-3
Size:
1 mg
Storage conditions:
–20 ± 5 °C
MDL No.:
MFCD18782539
Protein/peptide name:
Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH Trifluoroacetate
Molecular weight:
1145.15
Sequence:
Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(Dnp)-OH
Molecular formula:
C₅₃H₆₄N₁₀O₁₉
Cat. no.:
M-2195.0001BA
Supplier No.:
M-2195.0001

Specifications

About this item

Specific highly fluorescent FRET substrate for the determination of caspase-1 (ICE) and caspase-1-like enzyme activities. Cleavage of Mca-YVADAPK(Dnp) at the P1 Asp residue results in a continuous fluorescent assay monitored at an emission wavelength of 392 nm. Caspase-3 (apopain, CPP-32) is only weakly active on this substrate. Both caspase-1 and caspase-3 are involved in apoptosis. A specific substrate for renal ACE 2.

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