Ac-Trp-Glu-His-Asp-AMC
Catalog #: I-1715.0005BA
Supplier: Bachem Americas
CAS Number:
Specifications
- CAS No.:189275-74-9
- Size:5 mg
- Storage conditions:–20 ± 5 °C
- MDL No.:MFCD01318829
- Protein/peptide name:Ac-Trp-Glu-His-Asp-AMC
- Molecular weight:784.78
- Sequence:Ac-Trp-Glu-His-Asp-AMC
- Molecular formula:C₃₈H₄₀N₈O₁₁
- Cat. no.:I-1715.0005BA
- Supplier No.:I-1715.0005
Specifications
About this item
With a kcat/Km of 3.3 · 10⁶ M⁻¹s⁻¹ the fluorogenic caspase-1 substrate Ac-WEHD-AMC is cleaved 50-fold more efficiently than I-1630. This result indicates that the optimal tetrapeptide recognition sequence for caspase-1 is Trp-Glu-His-Asp and not Tyr-Val-Ala-Asp.
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