Fmoc-Asp(OtBu)-(Dmb)Gly-OH | Proteins and Peptides

Fmoc-Asp(OtBu)-(Dmb)Gly-OH

Supplier: Bachem Americas

Fmoc-Asp(OtBu)-(Dmb)Gly-OH

Supplier: Bachem Americas

About this item

Please see also the corresponding amino acid derivatives Fmoc-(Dmb)Ala-OH (B-4175), Fmoc-(Dmb)Gly-OH (B-4170), Fmoc-(Hmb)Gly-OH (B-3490), and Fmoc-(Dmb)Leu-OH (B-4165).

Dmb backbone protection completely prevents base-catalyzed aspartimide formation of the Asp(OtBu)-Gly motif during Fmoc-SPPS. The Dmb moiety is readily introduced by coupling this Fmoc-dipeptide. Contrary to the Hmb derivative, cyclic lactones cannot be formed during activation.

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