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Specifications
- Antibody type:Primary
- Antigen name:Synaptophysin
- Clonality:Polyclonal
- Gene ID:6855
- Host:Rabbit
- Isotype:IgG
- Reactivity:Bovine
- Antigen symbol:SYP
- Conjugation:Unconjugated
- ImmunoChemistry:Yes
- ImmunoPrecipitation:Yes
- Size:100 μg
- Western blot:Yes
- Antigen synonyms:MRXSYP|major synaptic vesicle protein P38|MRX96
- Storage buffer:Tris/glycine buffer at pH 7.4, containing 0.02% sodium azide as preservative, cryo-protective agents, stabilizing proteins (BSA) and 30% glycerol.
- Storage temperature:Keep as concentrated solution. Store at 4 °C short term. For extended storage aliquot and store at –20 °C or below. Avoid freeze-thaw cycles.
- Concentration:1 mg/ml
- Immunogen:Synthetic peptide: FATCGSYSGELQLSVDCANKTE, corresponding to amino acids 41-62 of Human Synaptophysin.
- Tested applications:IHC, IP, WB
- Purification:Immunogen affinity purified
- Cat. no.:89367-388
- Supplier No.:GTX14692
Specifications
About this item
Synaptophysin is a 38kDa glycoprotein present in the membrane of neuronal presynaptic vesicles in brain, spinal cord, retina, vesicles of adrenal medulla, neuromuscular junctions, and endocrine cells. It is also expressed by neuroendocrine cells throughout the body, both normal and neoplastic. Synaptophysin is a useful marker for the identification of normal neuroendocrine cells and neuroendocrine neoplasms. This antibody reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary gland, thyroid, lung, pancreas, and gastointestinal mucosa. It also reacts with a wide spectrum of neuroendocrine neoplasms of neural type including neuroblastomas, ganglioneuroblastomas, ganglioneuromas, pheochromocytomas, chromaffin, and non-chromaffin paragangliomas.
IHC: Use at an assay dependent dilution. IP: Use at a dilution of 1/250. WB: Use at a dilution of 1/1000. Predicted molecular weight: 34 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Type: Primary
Antigen: SYP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Bovine