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N-Oleoyldopamine ≥98% (by TLC)

Supplier: Enzo Life Sciences

Endogenous TRPV1 agonist (Ki=36nM, EC50=36nM) with weak affinity for rat CB1 receptor (Ki=1.6µM). Potent inhibitor of 5-lipoxygenase (IC50=7.5nM) and of early and late events in TCR mediated T cell activation. Inhibits NF-κB dependent transcriptional activity without affecting either degradation of the cytoplasmic NF-κB inhibitory protein, IκBα, or DNA binding activity.

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