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ICRF-193 ≥95% (by HPLC)

ICRF-193 ≥95% (by HPLC)

Supplier: Enzo Life Sciences

A topoisomerase II inhibitor that does not cause DNA damage. Induces apoptosis in several cell lines including K562 and Molt-4 cells. Induces a G2 checkpoint that is associated with an ATR-dependent inhibition of polo-like kinase 1 (plk1) activity and a decrease in cyclin B1 phosphorylation.

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