You searched for: SB216763

Supplier: Enzo Life Sciences

Potent and selective inhibitor of GSK-3β (IC50=34nM). Stimulates glycogen synthesis in human liver cells and mimics other actions of insulin. Protects primary neurons from death induced by PI-3 kinase pathway inhibition suggesting therapeutic potential in neurodegenerative diseases and stroke. Reduces pulmonary inflammation and fibrosis in a mouse model.

Supplier: ABCAM INC CA

Potent and selective GSK3 inhibitor (Ki= 9 nM for GSK-3α). Has little activity against 24 other protein kinases (IC₅₀ >10 μM). Stimulates glycogen synthesis, gene transcription and is cardio- and neuroprotective.